Experimental mouse models of obesity have shed light into the mechanisms of weight gain and mechanisms to prevent it. The ability to manipulate the genome has led to the identification of neural and systemic causes of obesity. Moreover, targets for pharmaceutical agents have been identified in the mouse. Despite the number of existing genetic mouse models of obesity and the ability to create new ones, the ability to study the physiology of the mouse remains challenging. This is due to the small size of the mouse. This workshop will describe physiological, environmental, and surgical tools to study mouse models of obesity using state-of-the-art tools.
This TOS pre-conference workshop requires separate registration and space is limited. Lunch is provided. Presented at the Vanderbilt-NIH Mouse Metabolic Phenotyping Center on the Vanderbilt University Campus, 2.5 miles from the convention center.
Glucose Clamping the Conscious Mouse
David Wasserman, PhD
Energy Balance in the Mouse
John Lighton, PhD
Ambient Temperature as a Determinant of Mouse Metabolism
E. Matthew Morris, PhD
The Study of the Mouse Brain
Julio Ayala, PhD
Lunch and Tour of Vanderbilt-NIH Mouse Metabolic Phenotyping Center
Louise Lantier, PhD
Isotopic Methods for Metabolic Flux Analysis in the Mouse
Curtis Hughey, PhD
Bariatric Surgery in the Mouse
Vance L Albaugh, MD PhD