Racial and ethnic minorities are disproportionately affected by diabetes and obesity and their related complications. A myriad of factors contribute to these disparities, including genetics, environmental, behavioral, and social factors. This symposium will address issues related to racial disparities, including underlying genetic and metabolic contributors, while presenting evidence of disparate utilization and outcome benefits from clinical interventions. Finally, speakers will discuss policy and programmatic strategies to help reduce racial disparities in obesity and type 2 diabetes.