Background

Gastric Stenosis(GS) has been reported in 4% of Laparoscopic sleeve gastrectomy(LSG) cases. No studies have been suggested a possible correlation between the incidences of post LSG stricture and preoperative comorbidities. The aim of this study is to analyze the possible association between preoperative comorbidities and LSG stenosis in our bariatric population.

Methods

All patients who underwent primary or secondary LSG from January 2005 to March 2018 at our institution were retrospectively analyzed. The patient who developed GS postoperatively were matched with a controlled group for demographics and comorbidities. Categorical and nominal variables were analyzed with Chi-square and Independent T-test respectively.

Results

Of the 1878 patients reviewed, 10(0.53%) developed GS after LSG. These patients were matched with a control group in a 1:1 ratio. The mean age was 56.85±9.59 years, all females, and predominantly white (85%). After matching, BMI was found to be not statistically significant for GS (0.856). Preoperative diagnosis of T2DM, HTN and dyslipidemia were significant risks factors for GS, OR: 9(CI:0.809-100 and P=0.051), OR 13(CI: 1.19-152 and P=0.019) and OR 9(CI: 0.809-100 and P=0.051) respectively. Active smokers had increased risk for GS OR 5(0.655-38.15) when compared to never smokers. No statistical significance was found among patients with preoperative diagnosis of CKD, CAD, GERD or history of GI bleed, P=1.00, P= 0.305, P=0.639 and P=0.136 respectively (Table1).

Conclusions

Active and former smokers, T2DM, HTN, and dyslipidemia seems to be related to the incidence of post-LSG Gastric stenosis. Larger studies are necessary to corroborate these findings.